Malignancy Rate of Indeterminate Findings on FDG-PET/CT in Cutaneous Melanoma Patients

Background: The use of 18F-2-Fluor-2-desoxy-D-glucose Positron Emission Tomography/Computed Tomography FDG-PET/CT in clinical routine for staging, treatment response monitoring and post surveillance metastatic melanoma patients has noticeably increased due to significant improvement the overall survival rate patients. However, determining dignity findings with metabolic activity on can be sometimes challenging may need further investigation. Purpose: We aimed investigate malignancy indeterminate cutaneous Methods: This single-center retrospective study included who underwent between 2015 2017 reported as therefore requiring evaluation. was determined by subsequent imaging and, if required, additional histopathology. impact outcome management also reported. Results: A total 842 reports 244 were reviewed. Sixty included. Almost half all lymph nodes, lung nodules cerebral lesions. In total, 43.3% proved malignant. 81% malignant lesions metastases melanoma, while 19% could attributed other primary malignancies, such lung, breast, thyroid colorectal cancers. Malignant influenced 60% cases. Conclusion: Indeterminate should investigated. one out every two is majority are manifestations, however, a percentage, tumors found. Upon verification, patient changed most